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Orange Park: PICO

700 Blanding Blvd. Ste. 16 Orange Park, FL 32605


Evidence-based practice uses the PICO model for formulating a searchable question. 

PICO is a mnemonic used to describe the four elements of a good clinical foreground question:

P = Population/Problem

How would I describe the problem or a group of patients similar to mine?

I = Intervention

What main intervention, prognostic factor or exposure am I considering?

C = Comparison

Is there an alternative to compare with the intervention?

O = Outcome

What do I hope to accomplish, measure, improve or affect?

PICO Resources

Formulating a Clinical Question - an interactive tutorial from Boston University

Forming Focused Questions - PICO guide from the Centre for Evidence-Based Medicine (CEBM)

PICO Worksheet & Search Strategy- downloadable Word document provided by the University of Southern California

How to Form an Answerable Clinical Question - Cincinnati Children's walks you through an overview of the PICO method 

Seven Steps to the Perfect Pico a step-by-step guide to formulating an optimal PICO search 


Types of PICO Questions

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